ADA-friendly PDF: the science behindPositivePatient outcomes

The Science Behind Positive Patient Outcomes

Surface texture and porosity can play a crucial role in the body’s reaction to surgical implants, such as those used in abdominal wall reconstruction surgery. Known to be the predominant factor in the induced foreign body response, implant surface topography also has been shown to be a significant factor in how tissues affected by implanted materials behave both in vitro and in vivo. Certain implant materials may induce nonadherent fibrous capsules in soft tissue, which contract and stiffen over time. Initial stability and durability may be increased by selecting monofilament tissue implants that are strong, yet flexible, and offer large enough pore sizes to allow for cell infiltration into the implant as well as demonstrate the properties of the surrounding host tissue